Bioinformatics Hub

Projects

Examples of how we apply our expertise

Dec 2025

Multi-institute Patient Registry

Dr. Christina Thornton

Innovation

Developing tools and software that push bioinformatics forward

Engagements

Where we gather, teach, and collaborate with the community

Reproducibility

Open resources ensuring transparent and reproducible science

GitHub

Version-controlled code and workflows
for transparent collaboration.

Docker

Containerized environments to ensure consistent and reproducible analyses.

ShinyApps

Interactive applications to share and explore research findings.

Collaborators

Partners driving discovery together

Gut Microbiome

Dr. Braedon McDonald

Advancing best practices for microbiome xenografting in murine systems and bioinformatics to profile models against host properties.

Mucosal Immunology

Dr. Derek McKay

Defining IL4/IL6-driven regulatory macrophage programs and their role in modulating intestinal inflammation.

Single-cell Transcriptomics

Dr. Markus Geuking

Profiling thymic dendritic cells in germ-free, specific-pathogen-free, and microbiota-xenografted mice using single-cell technology.

Microbiome and Immunity

Dr. Kathy McCoy

Developing and operating IMC bioinformatics workflows to analyze microbe–immune interactions in controlled model systems.

Medical Informatics

Dr. Christina Thornton

Designing and building a patient registry, accessible online beyond hospital EMRs, to enable multi-institute research in bronchiectasis.

Bioinformatics is Medicine's New Backbone

In modern medicine, bioinformatics is essential for turning biological data into clinical insight. It enables the discovery of disease mechanisms, supports the development of targeted therapies, and helps personalize treatment by aligning interventions with a patient's unique molecular and cellular profile—bringing precision medicine to life.

Projects

Examples of how we apply our expertise

Cytokine-driven macrophages

Microbiota reproducibility

In Silico Immunopeptidomics

ONT Dorado Run Analyzer

Microbiota and Thymic DCs

Multi-institute Patient Registry

Innovation

Developing tools and software that push bioinformatics forward

Engagements

Where we gather, teach, and collaborate with the community

Reproducibility

Open resources ensuring transparent and reproducible science

GitHub

Docker

ShinyApps

Collaborators

Partners driving discovery together

Dr. Braedon McDonald

Dr. Derek McKay

Dr. Markus Geuking

Dr. Kathy McCoy

Dr. Christina Thornton

Bioinformatics is Medicine's New Backbone